Collin Kenney – Independent Project

Collin Kenney – Independent Project

Class of 2017

Introduction to Topic

Laboratory science the utilization of a specialized facility to conduct an experiment in order to answer a scientific question.  This generalized form of science is the basis of every type of science and is used to draw conclusions from any hypothesis and confirm or deny any type of scientific claim. This type of science provides evidence to all fields of science, and nearly all scientists are trained in techniques originating in the laboratory sciences. Laboratory is essentially the backbone of all other scientific fields and is taught to every scientist in every field. I chose this type of science to study because I find it very interesting to be hands on and involved with the physics science.

Project Description

My final innovations were all designed with the best interest of the scientist in mind. Two out of four innovations I created were based on trying to speed up, increase efficiency, and/or just better the overall feel of the cleanliness of the cleaning process. The self-cleaning biosafety cabinet is designed for the proper cleaning procedure for all inches of the cabinet to ensure proper decom before and after all experiments, while the Roomba is designed to make sure the lab itself is properly cleaned and non-contaminated to ensure the integrity of all experiments carried out there. The two other innovations were designed with efficiency in mind. The generator was to better a mobile scientists power supply and decrease the dependency on gas consumption and large, loud and dangerous generator use. The Pipette box was to prevent laboratory errors that come with the use of the multichannel pipette. The thought process behind the creation of my products

Experience Description

Shadowing at Aberdeen Proving Grounds was a very helpful and interesting place for this project. All the scientists are extremely helpful and were crucial in the completion of my innovations and shadowing experience. I spent most of my time following around and observing the duties of a level two scientist who was conducting growth and control confirmation tests (Berk).  I was able to also shadow a level one scientist and be hands on in the lab to conduct a library procedure (Karavis). Through my experience, I discovered that many if the experiments that we have run in the Biomed program are run with similar procedures as actual laboratory activities. Looking back on my experience it was extremely interesting to be able to do implement my pre-existing knowledge into a real-world experience. One of the major events that I felt was the coolest part was not even in the lab. One of the last days I was there I was taken to the Visitors center of APG because it was the centennial anniversary of the base. The center featured a section that laid out basically a walkthrough that showed off all the innovations that had come from scientists that work at APG. One of the innovations was the blue disinfecting goo that we have used for some labs. The other major event was a shark tank like conference where my mentor set up a conference of her team to analyze my biosafety cabinet. It was probably the coolest experience I have had through the biomed program. I was able to step up in front of specialists and pitch my innovation idea. They then helped me to perfect my product and make me think about things in ways that only people that work with the existing version of my product every day would think. Every little detail of my innovation was picked apart and then perfected. It was so cool to know that my idea was so greatly accepted by the people that would be using it if the product came to market. The final major part of my experience was being able to work with the level one scientist in the sequencing core because I was able to be hands on and conduct my own part of his experiment. This procedure was a PCR similar to what we did in MI except for his technology was able to speed the process up tenfold.  

Innovation Description

My project consisted of 4 innovative products, a customizable app/software, and a website to display and explain all my innovations. The first innovation that I came up with was a Self-Cleaning Biosafety cabinet. The idea for this product dawned on me in the first day in almost the first hour that I was there. I was watching my mentor clean out one of her cabinet so that she would be able conduct her experiment with assurance that no spores or anything could contaminate her procedures. She was also about 5’2” and couldn’t possibly clean the back of the cabinet or the sides properly due to her inability to reach into the cabinet far enough (Berk). This gave me the idea for the automated cleaning cabinet. I first conducted research of all of the major brands of biosafety cabinets and quickly learned that no current model of cabinet has an automated sprayer system as a part of the cabinet (Nuaire),  and after further research not even smaller companies or overseas companies had attempted this procedure. Once confirmed that my innovation didn’t exist I began work on my sketchup model. I first downloaded the basic biosafety cabinet from the warehouse and began ripping it apart into usable pieces. The workstation was completely removed from the model and it with my own adjustable table top with the hydraulic lifts attached to it. Next I created the actual sprayer device that would be mounted into the cabinet. Initially my idea was to have the sprayers be able to move back and forth, as well as up and down in the cabinet. My initial designs when executed did not allow for this motion, some part of it would have broken off for the mechanism to move in both directions. The first design was to have swing down rods that would allow the mechanism to be hidden away and then deploy for cleaning. The vertical rods would then be able to move the mechanism up and down while stationary poles along the top of the cabinet would allow it to easily glide back and forth along the top of the cabinet. However, when trying to create this type of movement ability I soon realized that the stationary poles along the top of the cabinet that the sprayers are attached to would allow it to be moved up and down. I tried to implement clips/lock and key type devices but that would make for a very unstable device. I then proceeded to draw this out on a white board and get all my thoughts out of my head to try and figure out how to make this can move in three dimensions.  When drawing out my design I was trying to think about any technology that already exists that I could borrow from that would help me to fix my dimensionality problem. It finally dawned on me, a crane game (EMH). As simple as this might sound, a crane game is essentially in the same family as my device. A mechanism that a user is controlling inside of a box and is designed to do a task that the user outside of the box couldn’t already do in the first place. With this new-found logic, I came up with my functional design for the sprayer mechanism. Two parallel rods will run along the top of the cabinet and the sprayer device will attach to them but not directly. A small trolley will connect the two together and give the sprayers the ability to move back and forth, but the trolley will also be equipped with a motor and coiled wire that will lower the sprayers up and down. Once I solved how the sprayers would move I next needed to design the sprayers themselves and where to put them. The three main sprayers were in my original design as 360 degree gyroscopic sprayers that would be able to fully spin all the way around to get the top bottom and most of the sides of the cabinet. After the shark tank experience described in my Experience Description. I figured out that the sides of the cabinets wouldn’t be disinfected enough so I added two more stationary sprayers to my design to fully clean the cabinet. The final aspect of the sprayer problem was disinfecting the entire mechanism itself because it would always be in the biosafety cabinet. Simple solution was to add two more micro sprayers that would disinfect the entirety of the mechanism specifically. The other parts of my innovation were small things like a catch pan for the tilting platform to drain into and then the removable containers that the catch pan drained into as well as the loading tanks on the side of the cabinet that would house all the cleaners that the scientist chooses to use. The only other large aspect of my project was how I ran the cleaning process. The whole system is operated by a tablet on the top of the cabinet with the customizable software that I created as another one of my innovations.

This software I created in PowerPoint in the form of an app design. This program also dawned on me “in the tank,” when many of the scientists questioned how the system would run and what it would use to clean (Gostomski). My software allows people to do custom wash cycles, chemicals, time, temperatures, saturation levels and even rest time, or for them to pick a stock wash cycle with all recommended settings. The programs final function is the ability to create and name a preset wash cycle with all your specific requirements. The process of making this app was very extensive in the amount of animations that I used to ensure that it would look like a real app that someone could use. Many of the buttons on the custom settings appear to function at a touch. The other time consuming part of this task was having to think through every single click a person might to and any problems, questions, or complaints that a person might have using this system. I demoed this app to anyone who cared (and some who didn’t) so that I could ensure that my app was the best that I could produce.

        Similar to this process was the building of my faux website. Initially when creating a website, I thought it would be a good idea to be try a create an actual website with a real domain and true website appearance. I quickly learned that the free programs to create websites were nothing but cumbersome, archaic programs that love to crash computers. I then took it upon myself to create another app-like PowerPoint that had the appearance and functionality of an app. Again, I had to put myself in a consumer’s shoes to know what exactly to have in my website. I did research by clicking through sales websites like amazon and eBay and made a list of the most important qualities they both shared that would be pertinent to creating a good sales website. My list included things like product description, photos, reviews, and related products. These were the core elements of successful websites that I took to design my website based off. My finished product when presented appears to be a website on a google chrome window. All the functionalities are listed on the main menu and you can click through all of them to be able to view, learn about, and even buy all my products straight off the sight. My website also talks about my faux company called Easy Science and gives quick access to the specific parts of my innovations that are the revolutionary aspects. My website follows a tie dye color scheme that subtly changes as you click through different layers of the cite.

        The inspiration for my next innovation was when I was working with my second mentor in the sequencing core of APG. When we were running the Library prep lab he was explaining to me that he usually is running dozens of these at a time and the process can be quite time consuming (Karavis). However, when running dozens of samples, he uses a multichannel pipette to speed things up a little. Although these speed things up, he complained that some of the pipette tips don’t engage properly and could either fall off during the experiment or wouldn’t take up the exact amount of sample needed for the experiment to be successful. This gave me the idea for my Multi-Channel Pipette tip loader. This box would take all the tips out of the disposable box and transfer them into spring loaded cassettes which would engage all the tips with equal pressure across all of them. This would help scientists to avoid the costly error of improperly engaged tips. Thinking through how to transfer all the tips at once into the cassettes was the most time-consuming part of this process. Transferring all the tips by hand would be terribly inefficient, and dumping them into a device would be grounds for an extra innovation and much more counter space than it is worth. So, my solution was to create a handheld spiky plastic transfer tool that would be placed on top of the open disposable box, engage all the tips, have the user flip the disposable box over and remove leaving all the tips on the plastic spikes, and then put the cassette box on top and the flip them back right side up. I also designed this box with space in mind so I designed it to connect all together as a single unit. The only problem with the innovation that was brought to my attention was the sterility of the tips and the re use of the same tool and cassettes. I simply would make them out of polypropylene plastic that is bleach resistant to disinfection is easy for all the pieces. (Gostomski & Berk)

        My third innovation was inspired by one of my mentor’s coworkers who had spent some time in mobile labs as part of the United States military research team (Thermos). He was talking to my mentor about some of the mobile labs that he got to work in as a part of that unit and was totally in love with the entire process for the mobile lab, except for one thing, power supply. Most of the mobile labs are set up and run off large gas generators in the middle of nowhere. These generators have all kinds of safety precautions and procedures that help to ensure that they won’t explode or kill anyone with the fumes produced (Thermos). He said that the setup process for the generators safety precautions sometimes took longer than the experiments themselves and the danger of a disaster was always on their mind. I took this as an opportunity for innovation. The first issue was being able to come up with a way to create electricity in a place that had none. After much deliberation, I thought that a turbine would be a good way to generate this electricity. My plan was to create a turbine that would attach to the axle of the mobile lab and generate electricity from the rotational energy like a wind turbine.(US Department of Energy)  The next problem was how to use this electricity, and this inspiration I got from DEWalt tools. Their new tool line is run off a universal battery that fits into all of their tools. The axle turbine will be used to charge three batteries of a similar concept for the military scientist to use in my brand of tools in their labs. Up to four of these turbines could be implemented on each mobile lab which would allow for 12 batteries to be available for use at all times. When I was explaining my idea to him he questioned how the scientist would access these packs and how long they could hold a charge. To answer this I designed my turbines to have extended wires that connect to a charging port for these packs on the outside of the van above the wheel well. All the person would need to do is walk outside, grab a pack, and come back in and hook it up. To account for the longevity of the batteries, I would design them to be able to function in the 2 or three-hour range and I also added a backup power reserve that could charge the batteries while the vehicle is stopped for an extended period of time. This reserve would be charged with the batteries when in motion and hold hours of extra charge on it.

        My final innovation was the simplest of them all, a laboratory Roomba. My mentor had mentioned that the floors of the labs were so disgusting because they didn’t have a way to properly clean the floors without creating aerosols that could hinder laboratory results with contamination, or possible harmful aerosols that could impact the health of everyone working (Berk). I jokingly said that they should invest in a Roomba but learned that Roombas don’t have an airtight seal on them and would create aerosols same as mopping or sweeping. Also, it would have to be HEPA filtered to be in a lab. So, my innovation was a Roomba with an airtight rubber seal around the edge of it and adding double HEPA filters to the vacuum exhaust. I also added alcohol/bleach sprayers and air dryers to disinfect the floor after it was vacuumed. This device would be self-contained and automated so you could just set it and leave the lab when you’re done and your lab is clean when you get back.

Project Topic

Introduction to Topic

Laboratory science the utilization of a specialized facility to conduct an experiment in order to answer a scientific question.  This generalized form of science is the basis of every type of science and is used to draw conclusions from any hypothesis and confirm or deny any type of scientific claim. This type of science provides evidence to all fields of science, and nearly all scientists are trained in techniques originating in the laboratory sciences. Laboratory is essentially the backbone of all other scientific fields and is taught to every scientist in every field. I chose this type of science to study because I find it very interesting to be hands on and involved with the physics science.

Project Overview

Project Description

My final innovations were all designed with the best interest of the scientist in mind. Two out of four innovations I created were based on trying to speed up, increase efficiency, and/or just better the overall feel of the cleanliness of the cleaning process. The self-cleaning biosafety cabinet is designed for the proper cleaning procedure for all inches of the cabinet to ensure proper decom before and after all experiments, while the Roomba is designed to make sure the lab itself is properly cleaned and non-contaminated to ensure the integrity of all experiments carried out there. The two other innovations were designed with efficiency in mind. The generator was to better a mobile scientists power supply and decrease the dependency on gas consumption and large, loud and dangerous generator use. The Pipette box was to prevent laboratory errors that come with the use of the multichannel pipette. The thought process behind the creation of my products

Experience

Experience Description

Shadowing at Aberdeen Proving Grounds was a very helpful and interesting place for this project. All the scientists are extremely helpful and were crucial in the completion of my innovations and shadowing experience. I spent most of my time following around and observing the duties of a level two scientist who was conducting growth and control confirmation tests (Berk).  I was able to also shadow a level one scientist and be hands on in the lab to conduct a library procedure (Karavis). Through my experience, I discovered that many if the experiments that we have run in the Biomed program are run with similar procedures as actual laboratory activities. Looking back on my experience it was extremely interesting to be able to do implement my pre-existing knowledge into a real-world experience. One of the major events that I felt was the coolest part was not even in the lab. One of the last days I was there I was taken to the Visitors center of APG because it was the centennial anniversary of the base. The center featured a section that laid out basically a walkthrough that showed off all the innovations that had come from scientists that work at APG. One of the innovations was the blue disinfecting goo that we have used for some labs. The other major event was a shark tank like conference where my mentor set up a conference of her team to analyze my biosafety cabinet. It was probably the coolest experience I have had through the biomed program. I was able to step up in front of specialists and pitch my innovation idea. They then helped me to perfect my product and make me think about things in ways that only people that work with the existing version of my product every day would think. Every little detail of my innovation was picked apart and then perfected. It was so cool to know that my idea was so greatly accepted by the people that would be using it if the product came to market. The final major part of my experience was being able to work with the level one scientist in the sequencing core because I was able to be hands on and conduct my own part of his experiment. This procedure was a PCR similar to what we did in MI except for his technology was able to speed the process up tenfold.  

Innovation

Innovation Description

My project consisted of 4 innovative products, a customizable app/software, and a website to display and explain all my innovations. The first innovation that I came up with was a Self-Cleaning Biosafety cabinet. The idea for this product dawned on me in the first day in almost the first hour that I was there. I was watching my mentor clean out one of her cabinet so that she would be able conduct her experiment with assurance that no spores or anything could contaminate her procedures. She was also about 5’2” and couldn’t possibly clean the back of the cabinet or the sides properly due to her inability to reach into the cabinet far enough (Berk). This gave me the idea for the automated cleaning cabinet. I first conducted research of all of the major brands of biosafety cabinets and quickly learned that no current model of cabinet has an automated sprayer system as a part of the cabinet (Nuaire),  and after further research not even smaller companies or overseas companies had attempted this procedure. Once confirmed that my innovation didn’t exist I began work on my sketchup model. I first downloaded the basic biosafety cabinet from the warehouse and began ripping it apart into usable pieces. The workstation was completely removed from the model and it with my own adjustable table top with the hydraulic lifts attached to it. Next I created the actual sprayer device that would be mounted into the cabinet. Initially my idea was to have the sprayers be able to move back and forth, as well as up and down in the cabinet. My initial designs when executed did not allow for this motion, some part of it would have broken off for the mechanism to move in both directions. The first design was to have swing down rods that would allow the mechanism to be hidden away and then deploy for cleaning. The vertical rods would then be able to move the mechanism up and down while stationary poles along the top of the cabinet would allow it to easily glide back and forth along the top of the cabinet. However, when trying to create this type of movement ability I soon realized that the stationary poles along the top of the cabinet that the sprayers are attached to would allow it to be moved up and down. I tried to implement clips/lock and key type devices but that would make for a very unstable device. I then proceeded to draw this out on a white board and get all my thoughts out of my head to try and figure out how to make this can move in three dimensions.  When drawing out my design I was trying to think about any technology that already exists that I could borrow from that would help me to fix my dimensionality problem. It finally dawned on me, a crane game (EMH). As simple as this might sound, a crane game is essentially in the same family as my device. A mechanism that a user is controlling inside of a box and is designed to do a task that the user outside of the box couldn’t already do in the first place. With this new-found logic, I came up with my functional design for the sprayer mechanism. Two parallel rods will run along the top of the cabinet and the sprayer device will attach to them but not directly. A small trolley will connect the two together and give the sprayers the ability to move back and forth, but the trolley will also be equipped with a motor and coiled wire that will lower the sprayers up and down. Once I solved how the sprayers would move I next needed to design the sprayers themselves and where to put them. The three main sprayers were in my original design as 360 degree gyroscopic sprayers that would be able to fully spin all the way around to get the top bottom and most of the sides of the cabinet. After the shark tank experience described in my Experience Description. I figured out that the sides of the cabinets wouldn’t be disinfected enough so I added two more stationary sprayers to my design to fully clean the cabinet. The final aspect of the sprayer problem was disinfecting the entire mechanism itself because it would always be in the biosafety cabinet. Simple solution was to add two more micro sprayers that would disinfect the entirety of the mechanism specifically. The other parts of my innovation were small things like a catch pan for the tilting platform to drain into and then the removable containers that the catch pan drained into as well as the loading tanks on the side of the cabinet that would house all the cleaners that the scientist chooses to use. The only other large aspect of my project was how I ran the cleaning process. The whole system is operated by a tablet on the top of the cabinet with the customizable software that I created as another one of my innovations.

This software I created in PowerPoint in the form of an app design. This program also dawned on me “in the tank,” when many of the scientists questioned how the system would run and what it would use to clean (Gostomski). My software allows people to do custom wash cycles, chemicals, time, temperatures, saturation levels and even rest time, or for them to pick a stock wash cycle with all recommended settings. The programs final function is the ability to create and name a preset wash cycle with all your specific requirements. The process of making this app was very extensive in the amount of animations that I used to ensure that it would look like a real app that someone could use. Many of the buttons on the custom settings appear to function at a touch. The other time consuming part of this task was having to think through every single click a person might to and any problems, questions, or complaints that a person might have using this system. I demoed this app to anyone who cared (and some who didn’t) so that I could ensure that my app was the best that I could produce.

        Similar to this process was the building of my faux website. Initially when creating a website, I thought it would be a good idea to be try a create an actual website with a real domain and true website appearance. I quickly learned that the free programs to create websites were nothing but cumbersome, archaic programs that love to crash computers. I then took it upon myself to create another app-like PowerPoint that had the appearance and functionality of an app. Again, I had to put myself in a consumer’s shoes to know what exactly to have in my website. I did research by clicking through sales websites like amazon and eBay and made a list of the most important qualities they both shared that would be pertinent to creating a good sales website. My list included things like product description, photos, reviews, and related products. These were the core elements of successful websites that I took to design my website based off. My finished product when presented appears to be a website on a google chrome window. All the functionalities are listed on the main menu and you can click through all of them to be able to view, learn about, and even buy all my products straight off the sight. My website also talks about my faux company called Easy Science and gives quick access to the specific parts of my innovations that are the revolutionary aspects. My website follows a tie dye color scheme that subtly changes as you click through different layers of the cite.

        The inspiration for my next innovation was when I was working with my second mentor in the sequencing core of APG. When we were running the Library prep lab he was explaining to me that he usually is running dozens of these at a time and the process can be quite time consuming (Karavis). However, when running dozens of samples, he uses a multichannel pipette to speed things up a little. Although these speed things up, he complained that some of the pipette tips don’t engage properly and could either fall off during the experiment or wouldn’t take up the exact amount of sample needed for the experiment to be successful. This gave me the idea for my Multi-Channel Pipette tip loader. This box would take all the tips out of the disposable box and transfer them into spring loaded cassettes which would engage all the tips with equal pressure across all of them. This would help scientists to avoid the costly error of improperly engaged tips. Thinking through how to transfer all the tips at once into the cassettes was the most time-consuming part of this process. Transferring all the tips by hand would be terribly inefficient, and dumping them into a device would be grounds for an extra innovation and much more counter space than it is worth. So, my solution was to create a handheld spiky plastic transfer tool that would be placed on top of the open disposable box, engage all the tips, have the user flip the disposable box over and remove leaving all the tips on the plastic spikes, and then put the cassette box on top and the flip them back right side up. I also designed this box with space in mind so I designed it to connect all together as a single unit. The only problem with the innovation that was brought to my attention was the sterility of the tips and the re use of the same tool and cassettes. I simply would make them out of polypropylene plastic that is bleach resistant to disinfection is easy for all the pieces. (Gostomski & Berk)

        My third innovation was inspired by one of my mentor’s coworkers who had spent some time in mobile labs as part of the United States military research team (Thermos). He was talking to my mentor about some of the mobile labs that he got to work in as a part of that unit and was totally in love with the entire process for the mobile lab, except for one thing, power supply. Most of the mobile labs are set up and run off large gas generators in the middle of nowhere. These generators have all kinds of safety precautions and procedures that help to ensure that they won’t explode or kill anyone with the fumes produced (Thermos). He said that the setup process for the generators safety precautions sometimes took longer than the experiments themselves and the danger of a disaster was always on their mind. I took this as an opportunity for innovation. The first issue was being able to come up with a way to create electricity in a place that had none. After much deliberation, I thought that a turbine would be a good way to generate this electricity. My plan was to create a turbine that would attach to the axle of the mobile lab and generate electricity from the rotational energy like a wind turbine.(US Department of Energy)  The next problem was how to use this electricity, and this inspiration I got from DEWalt tools. Their new tool line is run off a universal battery that fits into all of their tools. The axle turbine will be used to charge three batteries of a similar concept for the military scientist to use in my brand of tools in their labs. Up to four of these turbines could be implemented on each mobile lab which would allow for 12 batteries to be available for use at all times. When I was explaining my idea to him he questioned how the scientist would access these packs and how long they could hold a charge. To answer this I designed my turbines to have extended wires that connect to a charging port for these packs on the outside of the van above the wheel well. All the person would need to do is walk outside, grab a pack, and come back in and hook it up. To account for the longevity of the batteries, I would design them to be able to function in the 2 or three-hour range and I also added a backup power reserve that could charge the batteries while the vehicle is stopped for an extended period of time. This reserve would be charged with the batteries when in motion and hold hours of extra charge on it.

        My final innovation was the simplest of them all, a laboratory Roomba. My mentor had mentioned that the floors of the labs were so disgusting because they didn’t have a way to properly clean the floors without creating aerosols that could hinder laboratory results with contamination, or possible harmful aerosols that could impact the health of everyone working (Berk). I jokingly said that they should invest in a Roomba but learned that Roombas don’t have an airtight seal on them and would create aerosols same as mopping or sweeping. Also, it would have to be HEPA filtered to be in a lab. So, my innovation was a Roomba with an airtight rubber seal around the edge of it and adding double HEPA filters to the vacuum exhaust. I also added alcohol/bleach sprayers and air dryers to disinfect the floor after it was vacuumed. This device would be self-contained and automated so you could just set it and leave the lab when you’re done and your lab is clean when you get back.

By | 2017-05-12T12:16:22+00:00 May 12th, 2017|Biomed Capstone Project 2017|0 Comments

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